Erythromycin as a Treatment of Diabetic Gastroparesis

Gastroparesis is a condition where the stomach muscles lose their flexibility and function to transport food from the stomach into the digestive tract. There are many causes of gastroparesis, including viral and bacterial diseases, and hypothyroidsim sclerdoma. Symptoms of gastroparesis is generally regarded as a stomach full of seriously ill, vomiting, heartburn and described. The most common cause of gastroparesis is diabetes. Treatments vary, but the use of a commonly prescribed erythromycin, an antibiotic.

Erythromycin

Erythromycin is used in an anti-infective to a variety of gastrointestinal diseases such as bacterial endogenous cardiac tits, chancroid, pneumonia, lymphogranuloma venereum, mycoplasma, otitis, pharyngitis, skin, soft tissue infections, syphilis, infections, infections of the upper respiratory tract, bronchitis, chlamydia, Lyme disease treatment and prevention of rheumatic fever. Not registered as a condition marked gastroparesis. Reglan (metocloparmide) is the only drug approved by the Food and Drug Administration approved users to treat gastroparesis.

Erythromycin Links

The Mylan School of Pharmacy at Duquesne University in Pittsburgh asked the question about the effectiveness of erythromycin in the treatment of gastroparesis, which causes includes cases of diabetes. They say the drug is used to treat gastroparesis in the coming years, because it increases the motility stimulating receptors in the stomach to move, the muscle contractions that food from the stomach into the digestive tract.

Dosage for gastroparesis

Dosage ranged from 50 to 250 mg three times a day, usually 30 minutes before meals. According to the University of Utah School of Medicine, erythromycin IV works better emptying of the stomach increases. In a study by the University, a group of patients received 250 mg of erythromycin and the other group received 1000 mg. The study showed no difference in efficacy between doses.

Collateral effects


Drugs.com after the drug has relatively few side effects are nausea, abdominal pain, diarrhea and vomiting, rash, fever, cardiac arrhythmias and hypotension (low blood pressure), when administered intravenously recurring nightmares.
     
Serious adverse events, allergic reactions, hives, including hives, itching or lack of air pressure, or tightness in the chest, swelling of the mouth, face, lips, bloody stools, hearing, irregular heartbeat, heart, muscle weakness, can signal red, swollen rash, diarrhea, abdominal pain or cramps, and yellowing of the skin or eyes.

Considerations


A study of the Mylan School of Pharmacy, 50-100 mg of erythromycin for 15-30 minutes before eating, published by the addition of a diet low in mass, since the short-term symptoms in most patients, but the relief was often short of time. His conclusion was that if it were used erythromycin for gastroparesis, there is little evidence of efficacy in the treatment of gastroparesis.

5 comments:

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