The Gastroparesis

A common complication of an upset stomach, delayed gastric emptying. Known as gastroparesis, which is manifested by nausea, bloating, vomiting, constipation or diarrhea. The situation may also occur at rest, leading to metabolic disorders (eg, blood sugar in patients with diabetes mellitus), in the absence of somatic symptoms or signs.

Gastroparesis is actually a common complication of diabetes mellitus, poorly managed, resulting in autonomic neuropathy. Problems caused by changes in gastric motility in a steady amount of gastric function. They consist of (1), and serves as a reservoir for absorption of liquids and solids (changing, for example, caused by resection of the stomach), (2) mixing and homogenization of food and (three) is a functional barrier can burn directly behind the bells mixed pyloric sphincter.

Disturbances due to the range of partial or total obstruction of the gastric emptying very quickly and usually cover the interference with the normal mechanisms that are controlled by these functions. This is the intrinsic contractility of smooth muscle of the stomach, the enteric nervous system, the autonomic nervous system control of intestinal function most affected by the program in question, and gut hormones.

Just because the pyloric sphincter, like all sphincters, once again, a tonic contraction with relaxation, intermittent transient loss of control leads to excessive vagal tone and symptoms of different degrees of gastric outlet obstruction. The enteric nervous system, such as neuropathy, diabetes mellitus and the surgical incision of the abdominal wall or on the trigger to empty the trunk vagal usually slow.

It is important to note that in some cases, the expected delay emptying symptoms due to rapid dehydration. For example, an excessive contraction of the pylorus are fully open, but so rare in the duodenum, the composition may be in a large cake out of a distension of the stomach chimes.

This cake can effectively through the intestinal malabsorption and diarrhea, resulting in characteristic symptoms of dumping syndrome can be treated. The hormones have a clearly defined role, but important in the regulation of gastrointestinal motility in health and disease. For example, the antibiotic erythromycin gastrointestinal hormone motilin recognized by the recipient, which affect metabolism.

Some patients with gastroparesis, a significant improvement of erythromycin analogs, in particular diseases to be associated with a partial obstruction of the stomach taken to have nausea, bloating and constipation, which was important.

Because patients are different than the intrinsic contribution, the program gastrointestinal, anxious, nervous, stand-alone program, the higher centers of the central nervous system, hormones and control of motility of the gastrointestinal tract, not all effective drugs for Most gastroparesis patients also have the same symptoms.

Complications of gastroparesis include the development of gastric bezoars receive the content, bacterial growth, control of blood sugar irregular nausea and vomiting and weight loss are low. The levels of blood sugar can cause or a consequence of gastric emptying are.

The growth of bacteria can cause diarrhea and malabsorption of both. For unknown reasons, the signs and symptoms of gastroparesis associated variable from person to person, as influenced by the time a certain person, and often poorly correlated with gastric emptying.

In some cases, serotonin antagonists reduce visceral perception may be a useful prokinetic for signs and symptoms.

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